Monday Night Football: Injury and fantasy news for 49ers vs. Vikings
Jack McKessy
Until Week 6, the San Francisco 49ers were a wagon, having won every regular season game since Week 7 of the 2022 season. They ran into injury trouble against the Cleveland Browns and took their first loss of the season, 19-17, on a missed field goal at the end of regulation.
Meanwhile, the Minnesota Vikings have suffered some bad injury luck of their own, though they've won two of their last three games, including a Week 6 matchup with the Bears in Chicago, 19-13.
Both teams are missing key players ahead of a Monday Night Football clash, which will have implications on the game's result and potential fantasy football matchups.
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Monday Night Football: injury reports for 49ers, Vikings
San Francisco 49ers:
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| Name | Position | Injury | Game status |
| Dre Greenlaw | LB | Hamstring | Questionable |
| Christian McCaffrey | RB | Oblique | Questionable |
| Trent Williams | OT | Ankle | Doubtful |
| Deebo Samuel | WR | Shoulder | Out |
Minnesota Vikings
| Name | Position | Injury | Game status |
| Akayleb Evans | CB | Oblique | Questionable |
| Jalen Nailor | WR | Hamstring | Questionable |
| Ezra Cleveland | G | Foot | Out |
| Justin Jefferson | WR | Hamstring | Out-IR |
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Monday Night Football injuries: fantasy football implications
Minnesota Vikings
With Jefferson missing time with his hamstring injury, expect a greater reliance on wide receivers Jordan Addison, K.J. Osborn and Brandon Powell. Tight end T.J. Hockenson might see a heavier share of targets as well.
San Francisco 49ers
Wide receiver Deebo Samuel will miss at least two weeks with a hairline fracture in his shoulder, which means quarterback Brock Purdy will have to rely on his other receivers. Brandon Aiyuk should see a heavier target share along with Jauan Jennings, Ray-Ray McCloud and tight end George Kittle.
McCaffrey, meanwhile, is dealing with an oblique injury. He's expected to play on Monday night, though backup Elijah Mitchell may get more carries to take the load off of McCaffrey.
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